Preparative Chromatography

Need a higher pressure to perform complex purifications?

The Interchim puriFlash® range of compact and reliable instruments fully covers your needs, from preparative to ultra-preparative chromatography. This thanks to the InterSoft X and Genius software; artificial intelligence that helps you make your purification a success!

Carry out complex purifications with confidence!

Below we highlight 3 puriFlash systems ranging in pressure from 125 bar to 400 bar.

specifications puriFlash 5.125

puriFlash 5.125

Designed for preparative chromatography, the puriFlash® 5.125 is ideally suited for purifications of complex matrices (natural products) and, of course, for less demanding customary applications.

This instrument opens the door for the purification of complex mixtures with its 125 bar and 250 mL/min. For the separation of compounds, it offers the possibility of working on columns of 10 μm in reverse phase and 5 μm normal phase with close retention times.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tank
  • 1 integrated column holder
  • 1 integrated mounting for Dry Load
  • Flow range: 250 mL/min
  • Optimal flow rate for columns with an internal diameter of up to 80 mm
  • Maximum pressure: 125 bar
  • Quaternary gradient valve
  • Exhauster
  • Wash Discs
  • Wash pump for water circulation to prevent crystal deposition on the pump pistons (included in PWD package)
  • Flow range: 250 mL/min
  • Optimal flow rate for columns with an internal diameter of up to 80 mm
  • Maximum pressure: 125 bar
  • Quaternary gradient valve
  • Exhauster
  • Wash Discs
  • Wash pump for water circulation to prevent crystal deposition on the pump pistons (included in PWD package)
  • UV detector 200-400 nm
  • “DAD” technology
  • Multi-wavelength and scan over a band of 200 nm (or 600 nm with UVextended pack)
  • Spectral visualization and confirmation of purity
  • Optical light path cell: 0.3mm
  • Integrated ELSD detector (included in iELSD pack)
specifications puriFlash 5.250

puriFlash 5.250 – small but limitless

Experience its unique performance under all conditions. The puriFlash® 5.250 adapts to all requirements of routine preparative chromatography, complex mixtures, separation of impurities for later detection, trace enrichment, etc.

Maximum versatility and flexibility
You will find that this system will be an indispensable support in your laboratory. It has been thought out down to the smallest detail to meet all your needs. The only question you will ask yourself during its operation is how you managed without it for so long.
The system is ready at any time to start multiple purifications in normal or in Reversed Phase, flash chromatography or preparative HPLC. With its pressure of 250 bar and flow of 250 mL/min, it can handle it all; from routine purification to complex purification.

Purify with confidence

This instrument is designed to operate with complete confidence 24 hours a day, 7 days a week, with minimal maintenance. It is equipped with numerous leak detectors (RFID technology) for automatic detection of columns, Dry Load, injection loops and racks. In short, it is packed with technology.
All this allows you to concentrate on synthesis steps. It has never been easier to perform purifications.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tank
  • 2 integrated column supports
  • 2 integrated Dry Load supports
  • Flow: 250 mL/min
  • Optimal flow rate for columns with an internal diameter of up to 80 mm
  • Maximum pressure: 250 bar
  • Quaternary gradient valve
  • Exhauster
  • Wash Discs
  • Wash pump for water circulation to prevent crystal deposition on the pump pistons (included in PWD package)
  • Injection mode: liquid or solid
  • “Load & Go” technology: with automatic 10-way valve allowing the use of staggered Dry Loads or injection loops for more efficient injection
  • RFID technology: automatic detection of the Dry Loads and the injection loops
  • 2 mL and 5 mL stainless steel injection loops
  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in the UVextended pack)
  • “DAD” technology
  • Multi-wavelength and scan collection over a band of 200 nm (or 600 nm with the UVextended pack)
  • Spectral visualization and confirmation of purity
  • Optical light path cell: 0.3mm
  • Integrated ELSD detector (included in the iELSD pack)
specifications puriFlash 5.400

puriFlash 5.400 – Ultra Flash chromatografie

This instrument is designed to excel in method development and chromatography of rare and high quality sample material.

Push the limits of purification
If you strive for excellence, the puriFlash® 5,400 is perfect for you; from method development on an analytical column to chromatography by preparative HPLC. In addition to the unparalleled performance of this ultra Flash chromatography system, performing these steps on one device offers you greater flexibility, significant time savings, and increased productivity.

The PuriFlash® 5,400 with its maximum pressure of 400 bar is also compatible with the use of sub-2 micron columns for maximum separation efficiency. This means that you have access to ultra-purification for the purification of rare and high-value products.

Your products are valuable – make sure you never lose them
The level detectors for Solvents provide optimum safety. You are warned before your bottles are empty, preventing air from entering your preparative HPLC columns. RFID technology also prevents any risk of error by automatically detecting loops, Dry Loads, columns and racks on the system.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tank
  • 2 integrated column supports
  • 2 integrated Dry Load supports
  • Flow: 125 mL/min
  • Optimal flow rate for columns with an internal diameter of up to 60 mm
  • Maximum pressure: 400 bar
  • Quaternary gradient valve
  • Exhauster
  • Wash Discs
  • Wash pump for water circulation to prevent crystal deposition on the pump pistons (included in PWD package)
  • Injection mode: liquid or solid
  • “Load & Go” technology: with automatic 10-way valve allowing the use of staggered Dry Loads or injection loops for more efficient injection
  • RFID technology: automatic detection of the Dry Loads and the injection loops
  • stainless steel injection loops
  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in Pack-UVextended)
  • “DAD” technology
  • Multi-wavelength and scan collection over a band of 200 nm (or 600 nm with Pack-UVextended)
  • Spectral visualization and confirmation of purity
  • Optical light path cell: 1.0mm
  • Integrated ELSD detector (included in the iELSD package)

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